Economic traits are quantitative traits and are mostly controlled by a large number of genes. Some thesegenes tend to have a large effect on quantitative traits in cattle and are known as major genes primarilylocated at quantitative traits loci (QTL). However, in practice, QTL is linked to allele associates of the genecontrolling traits of interest. It is hypothesized that if QTL explaining a part of genetic differences betweenanimals are detected, the effect of the genes located at QTL could assist in estimating an animal’s truegenetic value. Therefore, QTL information could probably provides accuracy of breeding value estimation aswell as more genetic gain through selection of animals at relatively younger age. Marker assisted selection(MAS) is the indirect selection process where a quantitative trait of economic importance is selected not justbased on the trait itself but also on the basis of marker linked to QTL. MAS could be useful for traits thatare difficult to measure, exhibit low heritability, and are expressed late in development. Major genes whichare responsible for QTL could possibly be identified first by using different techniques such as geneexpression analysis and QTL mapping. Thereafter, the information generated could be implemented for MASin estimating breeding value. In this review we focused on delivering genome information into Hanwoobreeding program.